[HTML][HTML] Injectable poloxamer hydrogels for local cancer therapy

AC Marques, PC Costa, S Velho, MH Amaral - Gels, 2023 - mdpi.com
… (PT) injections allow high concentrations of therapeutic … promote retention of free or
encapsulated drugs at the tumor … thermoresponsive polymers, poloxamer-based hydrogels are …

[HTML][HTML] Injectable Thermoresponsive Hydrogels for Cancer Therapy: Challenges and Prospects

S Tanga, M Aucamp, P Ramburrun - Gels, 2023 - mdpi.com
… and into the systemic circulation via the high-pressure flow in the … chemotherapeutics into
poloxamer-based hydrogels is therefore … core, which helps to encapsulate hydrophobic drugs. …

Development of a Chemoablative, Thermoresponsive Hydrogel as a Drug Delivery Platform for Lung Cancer Applications

S Rossi - 2018 - repository.rcsi.com
… of the award of a higher degree of Doctor of Philosophy is my … Distribution of the injected
thermoresponsive hydrogel in an ex … the behaviour of the lead thermoresponsive hydrogels. …

[HTML][HTML] In situ hydrogel formulation for intra-articular application of diclofenac sodium-loaded polymeric nanoparticles

B Küçüktürkmen, UC Öz, A Bozkir - Turkish journal of …, 2017 - ncbi.nlm.nih.gov
… 188 polymers in thermosensitive hydrogel formulations due to … Poloxamer-based hydrogels
are biocompatible and can be … The highest encapsulation efficiency was obtained with F6 …

Rheological and drug delivery characteristics of poloxamer-based diclofenac sodium formulations for chronic wound site analgesia

J Russo, J Fiegel, NK Brogden - Pharmaceutics, 2020 - mdpi.com
… Poloxamer 407, a thermosensitive polymer that is a liquid at low temperatures but gels at
higher … Additionally, poloxamer 407 has been studied for use in a vehicle for local injection of a …

Novel in situ forming hydrogel microneedles for transdermal drug delivery

A Sivaraman, AK Banga - Drug delivery and translational research, 2017 - Springer
… -ionic triblock amphiphilic thermosensitive copolymer, poloxamer… in injectable routes where
the liquid form was injected and … -gel transition property of poloxamer-based formulation was …

Quercetin Loaded Cationic Solid Lipid Nanoparticles in a Mucoadhesive In Situ Gel—A Novel Intravesical Therapy Tackling Bladder Cancer

S Shawky, S Makled, A Awaad, N Boraie - Pharmaceutics, 2022 - mdpi.com
… ], etoposide [26] and doxorubicin [27], due to the high solubility of … entrapment efficiency for
various lipophilic drugs and ensure … Different poloxamer based in situ gels were prepared and …

Characterization of thermosensitive gels for the sustained delivery of dexketoprofen trometamol for dermal applications

Ö Çulcu, E Tunçel, Sİ TAMER… - Journal of Gazi University …, 2020 - dergipark.org.tr
thermosensitive properties of poloxamer 338. Also released amount of DEX were decreased
due to the use of high … vitro drug release profiles of poloxamer based formulations were fit to …

Glaucoma: current treatment and impact of advanced drug delivery systems

KS Yadav, R Rajpurohit, S Sharma - Life sciences, 2019 - Elsevier
… lipid lead to increase in encapsulation efficiency. This formulated … combination of hydrogels
ie thermosensitive elastin and silk … able to inject free drug as well as encapsulated nanosized …

Mucoadhesive, thermoreversible hydrogel, containing tetracaine-loaded nanostructured lipid carriers for topical, intranasal needle-free anesthesia

GMF Calixto, BV Muniz, SR Castro, JSM de Araujo… - Pharmaceutics, 2021 - mdpi.com
… indicated preference for the traditional injection [1]. Other … it in a mucoadhesive and
thermosensitive hydrogel which was … Tetracaine quantification during the encapsulation efficiency